Beckman CD3 complex has 5 polypeptides (γ, δ, ε, ζ, η); ζ forms homodimers. Activates T cells via antigen-MHC binding in T cells/thymocytes.

Beckman Cd3ζ see tcrζ in human non-cd antigens section. The cd3 antigen is a complex of 5 invariable polypeptidic chains, γ, δ, ε, ζ and η, whose molecular weights are respectively 25-28, 21, 20, 16 and 22 kda. The ζ chain occurs in the cd3 complex as a disulphide linked homodimer or as a heterodimer with the η chain. Cd3 is part of a bigger complex which includes the t cell receptor (tcr). This complex is expressed by mature t cells and by thymocytes. T cell activation may be induced when a foreign antigen is presented to the tcr through mhc complex. *Alexa fluor and pacific blue are registered trademarks of molecular probes, inc. - BCKM (Additional S&H or Hazmat Fees May Apply)