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Beckman Cd80-Apc, Mab104, 0.5 mL, ASR
List Price $619.00 Your Price $619.00
Beckman Cd80-Apc, 0.5ml Asr - BCKM (Additional S&H or Hazmat Fees May Apply)
NETA PART: BCKM-B30642
MFG.PART: B30642
UNSPSC: 41116001
Manufacturer: Beckman Coulter
The CD80 antigen (B7, BB1) is a highly glycosylated single-chain protein. Its extracellular domain consists of two Ig-like domains. This 60 kDa molecule shares with CD86 the capability to be the ligand for two structurally similar molecules expressed on T lymphocytes, CD28 and CD152 (CTLA-4). CD80 antigen is expressed on in vitro activated B lymphocytes after 24h stimulation and at maximal level 48-72h post activation. It is not expressed on the majority of resting B cells from peripheral blood but identifies a subpopulation of B cells that has been previously activated. The antigen is also expressed by HTLV-1 transformed T cells and activated monocytes. CD80 binding provides co-stimulatory signals for T cell activation.
Product Specifications
| Target Species | Human |
| Specificity | CD80 |
| Other Names | B7, B7-1, BB1, CD80 |
| Fluorochrome | APC |
| Regulatory Status | ASR |
| Size | 0.5 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | MAB104 |
| Isotype | IgG1 Mouse |
| Clone Description | The MAB104 monoclonal antibody reacts with in vitro activated B lymphocytes, some B cell lines, and weakly with a small proportion of non-activated B cells. This antibody also reacts with activated T cells but not with peripheral monocytes and T cells. |
| SKU | BCKM-B30642 |
|---|---|
| Supplier Part Number | B30642 |
| UM | EA |
| UNSPSC | 41116001 |
| Manufacturer | Beckman Coulter |
| ProductLine | BCKM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 21 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |