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Beckman Cd61-Unlb, Sz21, 0.2 Mg, Ruo
List Price $619.00 Your Price $619.00
Beckman Cd61, 0.2mg, Ruo - BCKM (Additional S&H or Hazmat Fees May Apply)
NETA PART: BCKM-IM0540
MFG.PART: IM0540
UNSPSC: 41116001
Manufacturer: Beckman Coulter
The CD61 antigen (platelet glycoprotein GPIIIa) is the 110 kDa integrin β3 subunit, con-covalently associated with the integrin αIIb chain (CD41, platelet GPIIb) to form the GPIIb-IIIa complex (αIIb-β3 integrin). Independently of CD41, CD61 is also associated with the integrin αV (CD51) to form the vitronectin receptor. CD41/CD61 is expressed only by platelets and megakaryocytes, whereas CD51/CD61 is found on osteoclasts, endothelial cells, macrophages, fibroblasts, smooth muscle, synovial lining cells and renal glomeruli.
Product Specifications
| Target Species | Human |
| Specificity | CD61 |
| Other Names | b3 integrin, beta3 integrin, CD61, Glycoprotein IIIa, gpIIIa, Integrin beta3-chain |
| Fluorochrome | UNLB |
| Regulatory Status | RUO |
| Size | 0.2 mg |
| Format | Freeze-dried |
| Clone | SZ21 |
| Isotype | IgG1 Mouse |
| Clone Description | The SZ21 antibody is specific for the PlA1, not the PlA2 form of GPIIIa. It inhibits platelet aggregation and secretion induced by collagen, arachidonic acid, and thrombin. This antibody also inhibits fibrinogen binding to human platelets induced by ADP, arachidonic acid and PAF. |
| SKU | BCKM-IM0540 |
|---|---|
| Supplier Part Number | IM0540 |
| UM | EA |
| UNSPSC | 41116001 |
| Manufacturer | Beckman Coulter |
| ProductLine | BCKM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 21 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |