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Beckman Cd16-Pe, 3g8, 2 mL, ASR
List Price $895.62 Your Price $895.62
Beckman Cd16-Rpe, 2ml, Asr - BCKM (Additional S&H or Hazmat Fees May Apply)
NETA PART: BCKM-IM1238U
MFG.PART: IM1238U
UNSPSC: 41116001
Manufacturer: Beckman Coulter
The CD16 antigen is the low-affinity receptor for IgG (FcγRIII). The CD16 antigen exists in two different forms encoded by two different genes: FcγRIIIA (or III-2) and FcγRIIIB (or III-1). The genetic heterogeneity of CD16 generates alternative membrane-anchored molecules. One is a transmembrane form (FcγRIIIA, 50-65 kDa) expressed on NK cells, monocytes and macrophages. The other is a glycosylphosphatidylinositol (GPI)-anchored form (FcγRIIIB, 48 kDa) only expressed on neutrophils. It has been shown that the CD16 antigen can be non-covalently associated within the membrane of NK cells, to a disulfide-linked homo or heterodimer made from the 16 kDa CD3ζ chain and the FcεRIγchain.
Product Specifications
| Target Species | Human |
| Specificity | CD16 |
| Other Names | CD16, Fc gamma R IIIa&b, FCγRIII, FcγRIIIA/IIIB |
| Fluorochrome | PE |
| Regulatory Status | ASR |
| Size | 2 mL |
| Format | Liquid |
| Flow Product Line | IOTest |
| Clone | 3G8 |
| Isotype | IgG1 Mouse |
| Clone Description | The 3G8 monoclonal antibody is inappropriate for western Blot use. 3G8 binds to both isoforms of the CD16 molecule. |
| Cross Reactivity | Cynomolgus Monkey, Indian Rhesus, Hamadyras Baboon, Olive Baboon, Capuchin Monkey, Common Marmoset, Canine, Equine, Squirrel Monkey |
| SKU | BCKM-IM1238U |
|---|---|
| Supplier Part Number | IM1238U |
| UM | EA |
| UNSPSC | 41116001 |
| Manufacturer | Beckman Coulter |
| ProductLine | BCKM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 21 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |