Beckman CD10 (CALLA), 100 kDa protein, found on germinal B cells, neutrophils, bone marrow, and some epithelial cells.

Beckman The cd10 antigen is referred to as the common acute lymphoblastic leukemia antigen (calla). It is a type ii integral membrane protein of 100 kda, identified as the human membrane-associated neutral endopeptidase (ec3.4.24.11). It is expressed on uncommitted lymphoid precursors. Cd10 expression is lost as cells enter the t lineage. In the b lineage, cd10 expression is lost later in ontogeny, as cells acquire surface ig expression. It is also expressed on activated and proliferating b cells in the germinal center, and on neutrophils as well as on bone marrow stromal cells. It is also expressed on a number of other cells of epithelial origin. - BCKM (Additional S&H or Hazmat Fees May Apply)