Beckman TCR Ζ-Pe, 2h2d9 (Tia-2), 2 mL, ASR

The ζ subunit is a 16 kDa surface molecule associated with the T cell receptor. Its expression is restricted to T lymphocytes and NK cells. In T lymphocytes, the ζ subunit is expressed as a disulfide-linked homodimer of 32 kDa or as a disulfide-linked heterodimer with a 21 kDa subunit designated η. Both of these dimeric species are non-covalently associated with the remaining subunits of the CD3-TCR-antigen receptor complex. In NK cells, the ζ subunit is expressed as a disulfide-linked homodimer of 32 kDa or as a disulfide-linked heterodimer with a 12 kDa subunit. It is associated with the CD16 molecule (FcγRIII).