We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Beckman Cd208-Unlb, 104.G4, 0.2 Mg, Ruo
List Price $731.00 Your Price $731.00
Beckman Cd208 (Dc-Lamp), 0.2mg, Ruo - BCKM (Additional S&H or Hazmat Fees May Apply)
NETA PART: BCKM-IM3448
MFG.PART: IM3448
UNSPSC: 41116001
Manufacturer: Beckman Coulter
The DC-LAMP antigen (70-90 kDa) is a new member of the LAMP (lysosome-associated membrane protein) family. As other LAMP members such as CD68, DC-LAMP is a type I integral membrane protein of 416 amino acid residues, highly glycosylated (7 N- and some O- glycosylation sites), with 90% of the molecule located in the lumen of lysosomes. DC-LAMP is specifically expressed by those mature dendritic cells (DC) located in T cell areas of lymphoid tissues, which are known as interdigitating dendritic cells (IDC). A direct correlation between the expression of DC-LAMP and that of other maturation markers such as CD86 has been established. DC-LAMP first appears in the MHC Class II compartment, suggesting an important contribution of DC-LAMP to the processing of exogenous antigens.
Product Specifications
| Target Species | Human |
| Specificity | CD208 |
| Other Names | CD208, DC-LAMP, LAMP |
| Fluorochrome | UNLB |
| Regulatory Status | RUO |
| Size | 0.2 mg |
| Format | Liquid |
| Clone | 104.G4 |
| Isotype | IgG1 Mouse |
| Clone Description | In flow cytometry, the 104.G4 antibody shows intracytoplasmic staining of DCs derived either from CD34+ cell cultures activated with TNFα and CD40L, or from monocyte cultures activated with TNFα, LPS and CD40L. |
| SKU | BCKM-IM3448 |
|---|---|
| Supplier Part Number | IM3448 |
| UM | EA |
| UNSPSC | 41116001 |
| Manufacturer | Beckman Coulter |
| ProductLine | BCKM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 21 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |