Revvity Human Il17a/Il17ra Bindi

Revvity Interleukin 17a, A Pro-Inflammatory Cytokine, Belongs To A Family Of Six Cytokines; Il-17a, Il-17b, Il-17c, Il-17d, Il-E, And Il-17f. Il-17a Binds A Heterodimeric Cell Surface Receptor (Il-17ra/Il-17rc), Triggering A Signaling Cascade That Results In Nf-B Activation Which Leads To The Stimulation Of The Pro-Inflammatory Cytokines Il-6 And Il-8. Although This Cytokine Exerts A Protective Role Against Many Pathogens, The Overproduction Of Il-17a Is Associated With Autoimmune Diseases Such As Psoriasis, Rheumatid Arthritis, And Crohns Disease - PEGSK (Additional S&H Or Hazmat Fees May Apply)