Revvity Htrf Human Rig-I Binding Kit

Revvity A Fast And Easy Way To Identify New Binders To Human Rig-I. The Retinoic Acid-Inducible Gene I (Rig-I) Is A Cytosolic Pattern Recognition Receptor Which Is Known To Recognize Rna Pathogens In Cells. This Protein Is Involved In The Innate Immune System And Induces A Type 1 Interferon Response. The Rig-I Protein Recognizes Infected Cells By Detecting Viral Dsrna. Once Activated By A Dsrna, The N-Terminus Domain Of Rig-I Binds Mitochondrial Antiviral Signaling Proteins, Thereby Activating The Ifn-1 Signaling Pathway. - PEGSK (Additional S&H Or Hazmat Fees May Apply)