Revvity Human H232 Sting Binding Kit, 10000 Tests

Revvity A Fast And Easy Way To Identify New Binders To Human H232 Sting. Stimulator Of Interferon Genes (Sting), Also Known As Transmembrane Protein 173 (Tmem173), Is A Protein Playing A Major Role In Innate Immunity. The H232 Variant Is Found In 13.7% Of The World Population. Upon Intracellular Cytosolic Dna Release From Pathogens Such As Viruses And Bacteria, 2’-3’Cgamp Binds To Sting Protein And Triggers The Secretion Of Type 1 Interferon.  However, The H232 Variant Is Known To Poorly Bind 2-3cgamp And Other Natural Dinucleotides. The Quest For Molecules That Are Effective Against All Genetic Variants Has Become Crucial To Modulate Immunity In Autoinflammatory Diseases.S - PEGSK (Additional S&H Or Hazmat Fees May Apply)