Revvity Human Ctla4/Cd86 Biochemical Binding Assay, 500

Revvity Ctla4 (Cytotoxic T-Lymphocyte-Associated Protein 4), Also Known As Cd152, Is An Inhibitor Of The Immune Response Expressed By T Cells. Ctla4 And Cd28 (Stimulatory Checkpoints) Share The Same Ligands, Namely Cd80 (B7.1) And Cd86 (B7.2), With Ctla4 Displaying A Greater Affinity Than Cd28 For Both, Thus Creating Effective Ligand Binding Competition. Although Ctla4 Can Be Found On All T Cells, It Is Mainly Expressed On Treg (Regulatory T Cells), Where It Participates In Their Inhibition Of The Immune Response.S - PEGSK (Additional S&H Or Hazmat Fees May Apply)