Sigma-Aldrich Chloroacetyl Chloride 98%

Chloroacetyl chloride is used as a chlorinating agent, acylating agent, precursor to monochloroketene, and as a building block for cyclization.[1]

Chloroacetyl chloride causes the acylation of cyano-pyrazoline during the synthesis of secondary amine-substituted cyano-pyrazoline derivatives[2].

Chloroacetyl chloride can be used for chloroacetylation and chemical modification of poly(glycidyl methacrylate)[3]. Chloroacetyl chloride was used to study the in vitro metabolism of chloroacetamide herbicides by rat and human liver microsomes[4]. Chloroacetyl chloride was used in the synthesis of some novel quinoline derivatives having antileishmanial activity[5].