Sigma-Aldrich 2-Cyanoacetamide 99%

Cyanoacetamide is the starting reagent for vitamin B₆ synthesis[1]. It reacts with reducing carbohydrates in borate buffer to give intense fluorescence andis useful for the automated analysis of carbohydrates as borate complexes[2].

Cyanoacetamide is a highly reactive compound used as a reaction intermediate in condensation and substitution reactions. [3] [4]

Cyanoacetamide was used in spectrofluorimetric method for the determination of some antihistaminic H₁ receptor antagonist drugs such as ebastine, cetirizine dihydrochloride and fexofenadine hydrochloride[5]. It may be used in fluorometric determination of 3,4-dihydroxyphenylalanine[6]. It was used as post column fluorigenic derivatizing agent for the bio-analysis and pharmacokinetics of chitosan ester in rabbit serum[5].