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Sigma-Aldrich Azelaic Acid
List Price
$242.55
Your Price
$242.55
Sigma-Aldrich Azelaic Acid - SIAL (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
SIAL-11480-1KG
MFG.PART:
11480-1KG
UNSPSC:
12352100
Manufacturer:
Sigma-Aldrich
vapor density
6.5 (vs air)
Quality Level
200
vapor pressure
<1 mmHg ( 20 °C)
grade
technical
assay
~85% (GC)
bp
286 °C/100 mmHg (lit.)
mp
109-111 °C (lit.)
SMILES string
OC(=O)CCCCCCCC(O)=O
InChI
1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)
InChI key
BDJRBEYXGGNYIS-UHFFFAOYSA-N
Related Categories
Exclusive Savings
Organic Building Blocks
General description
Azelaic acid (Nonanedioic acid) is a naturally occurring saturated, nonphenolic compound isolated from cultures Pityrosporum ovale[1]. It is a therapeutic agent with well-known antibacterial properties[2].
Application
- A phase 3 randomized, double-blind, vehicle-controlled trial of azelaic acid foam 15% in the treatment of papulopustular rosacea: This study evaluates the efficacy and safety of a 15% azelaic acid foam in treating rosacea, demonstrating significant improvements in disease severity (Draelos et al., 2015).
- Comparison of the characteristics of transfersomes and protransfersomes containing azelaic acid: This research compares the properties of transfersome formulations with azelaic acid, highlighting their potential for enhanced delivery in dermatological applications (Rahmi and Pangesti, 2018).
- Enhancing the bioconversion of azelaic acid to its derivatives by response surface methodology: This article discusses optimizing the production of azelaic acid derivatives, which are crucial for cosmetic and pharmaceutical applications (Khairudin et al., 2018).
- Azelaic acid: a bio-based building block for biodegradable polymers: The study explores azelaic acid as a sustainable precursor for producing biodegradable polymers, pertinent to material science (Todea et al., 2021).
- Preparation and evaluation of azelaic acid topical microemulsion formulation: in vitro and in vivo study: This research presents a microemulsion formulation of azelaic acid, assessing its stability and skin permeability, critical for topical therapeutic applications (Hung et al., 2021).
Biochem/physiol Actions
Azelaic acid is a potent inhibitor of 5α-reductase activity[3]. It is a reversible competitive inhibitor of thioredoxin reductase in human melanoma cells[4].
pictograms
GHS07
signalword
Warning
hcodes
H315,H319
pcodes
P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
wgk_germany
WGK 1
ppe
Eyeshields, Gloves, type N95 (US)
| SKU | SIAL-11480-1KG |
|---|---|
| Featured | No |
| Supplier Part Number | 11480-1KG |
| UM | EA |
| UNSPSC | 12352100 |
| Manufacturer | Sigma-Aldrich |
| Temperature | room temp |
| Refrigerated-Frozen | N |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 10.000000 |
| Lead Time | 9 |
| Hazardous | Y |
| CAS Number | 123-99-9 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |