Sigma-Aldrich Anisole Reagentplus 99%

Anisole can be obtained from the reaction between methyl formate and sodium phenolate or potassium phenolate at high temperature and pressure.[1]

Anisole has been used as a dopant to improve the sensitivity of photoionization at atmospheric pressure, which can be used as a source in the detection of nonpolar compounds using liquid chromatography coupled with mass spectrometry.[2] It has also been used to improve the molecular fragmentation which further increases the background signal intensity in hyperthermal surface ionization source, when coupled with time-of-flight mass spectrometer.[3]

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